Recombinant Rabbit Macrophage metalloelastase (MMP12)

Code CSB-YP014659RB
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP014659RB
MSDS
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Source E.coli
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Code CSB-EP014659RB-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP014659RB
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP014659RB
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
MMP12
Uniprot No.
Alternative Names
MMP12; Macrophage metalloelastase; MME; EC 3.4.24.65; Matrix metalloproteinase-12; MMP-12
Species
Oryctolagus cuniculus (Rabbit)
Expression Region
101-464
Target Protein Sequence
RPVWRKHYIT YRIKNYTPDM KREDVEYAIQ KAFQVWSDVT PLKFRKITTG KADIMILFAS GAHGDYGAFD GRGGVIAHAF GPGPGIGGDT HFDEDEIWSK SYKGTNLFLV AVHELGHALG LDHSNDPKAI MFPTYGYIDL NTFHLSADDI RGIQSLYGGP EQHQPMPKPD NPEPTACDHN LKFDAVTTVG NKIFFFKDSF FWWKIPKSST TSVRLISSLW PTLPSGIEAA YEIGDRHQVF LFKGDKFWLI SHLRLQPNYP KSIHSLGFPD FVKKIDAAVF NPSLRKTYFF VDNLYWRYDE RREVMDAGYP KLITKHFPGI GPKIDAVFYF QRYYYFFQGP NQLEYDTFSS RVTKKLKSNS WFDC
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Gene References into Functions
  1. Gene expression profiling performed on tissues obtained from pulmonary sarcoidosis patients identified MMP12 as a potential pathogenic mediator of lung damage and/or remodeling and may serve as a marker for this disease. PMID: 19218196
Subcellular Location
Secreted, extracellular space, extracellular matrix.
Protein Families
Peptidase M10A family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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