Code | CSB-RA827961A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
IHC | 1:50-1:200 |
CHRM3 codes for M3-muscarinic receptor (M3R), the major mAChR expressed on smooth muscle and drives contractile responses in the ileum. The M3R receptor has been identified as the bonafide receptor responsible for the cholinergic regulation of glucose-induced insulin release. M3R has also been demonstrated to promote insulin release by decreasing the activity of the mitogen-activated protein kinase p38, which inhibits PKD1 in β cells. Cholinergic signaling via the M3R is necessary for optimal Th1 and Th2 adaptive immunity to infection.
CUSABIO designed the vector clones for the expression of a recombinant CHRM3 antibody in mammalian cells. The vector clones were obtained by inserting the CHRM3 antibody heavy and light chains into the plasma vectors. The recombinant CHRM3 antibody was purified from the culture medium through Affinity-chromatography. It can be used to detect CHRM3 protein from Human in the ELISA, WB, IHC.There are currently no reviews for this product.