Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Recombinant human Muscarinic acetylcholine receptor M3 protein (270-470AA)
Raised in :
Species Reactivity :
Tested Applications :
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Storage Buffer :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification method :
Antigen Affinity Purified
Muscarinic acetylcholine receptor M3,CHRM3
Target details :
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.