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Code | CSB-RA589492A0HU |
Size | US$350 |
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Have Questions? | Leave a Message or Start an on-line Chat |
Uniprot No. | P31689 | ||||||||
Target Names | DNAJA1 | ||||||||
Alternative Names | DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2), DNAJA1, DNAJ2 HDJ2 HSJ2 HSPF4 | ||||||||
Species Reactivity | Human | ||||||||
Immunogen | A synthesized peptide derived from human DNAJA1 | ||||||||
Immunogen Species | Homo sapiens (Human) | ||||||||
Conjugate | Non-conjugated | ||||||||
Clonality | Monoclonal | ||||||||
Isotype | Rabbit IgG | ||||||||
Clone No. | 23C6 | ||||||||
Purification Method | Affinity-chromatography | ||||||||
Concentration | It differs from different batches. Please contact us to confirm it. | ||||||||
Buffer | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | ||||||||
Form | Liquid | ||||||||
Tested Applications | ELISA, WB, IF, FC | ||||||||
Recommended Dilution |
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Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunofluorescence (IF) Protocol Flow Cytometry (FC) Protocol |
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Troubleshooting and FAQs | Antibody FAQs | ||||||||
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||||
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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Function |
Co-chaperone for HSPA8/Hsc70. Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis. Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV.
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Gene References into Functions |
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Subcellular Location | Membrane; Lipid-anchor. Cytoplasm. Microsome. Nucleus. Cytoplasm, perinuclear region. Mitochondrion. |
Tissue Specificity | Ubiquitous. Isoform 2 is highly expressed in testis and lung, but detected at low levels in thymus, prostate, colon and liver. |
Database Links |
HGNC: 5229 OMIM: 602837 KEGG: hsa:3301 STRING: 9606.ENSP00000369127 UniGene: Hs.445203 |