Recombinant Mouse C-C motif chemokine 3 protein(Ccl3) (Active)

In Stock
Code CSB-AP001221MO
Product Type Chemokine
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P10855
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered concentrated solution in 30 % Acetonitrile and 0.1 % TFA,Lyophilized
Alias Heparin-binding chemotaxis protein, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, SIS-alpha, Small-inducible cytokine A3
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The biological activity determined by a chemoattract bioassay using murine splenocytes is in a concentration range of 10-100 ng/ml.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence APYGADTPTA CCFSYSRKIP RQFIVDYFET SSLCSQPGVI FLTKRNRQIC ADSKETWVQE YITDLELNA
Research Area Immunology
Source E.coli
Gene Names Ccl3
Expression Region 24-92aa
Tag Info Tag-Free
Mol. Weight 7.9 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3290382; 2521353; 2216738; 2784565; 2033269; 10438970; 3279154
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Function Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils.
Subcellular Location Secreted
Protein Families Intercrine beta (chemokine CC) family
Tissue Specificity Expressed in lung, spleen, and pancreas.
Database Links

KEGG: mmu:20302

STRING: 10090.ENSMUSP00000001008

UniGene: Mm.1282

Pathway Chemokine signaling pathway
Toll-like receptor signaling pathway

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