Recombinant Human Superoxide dismutase [Cu-Zn] protein(SOD1) (Active)

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Code CSB-AP000121HU
Product Type Enzyme
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P00441
Lead Time 5-10 business days
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias EC 1.15.1.1, hSod1
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The potency per mg was determined by Pyrogallic Acid method and was found to be more than 1.0x104 IU/mg.
Purity >95% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence MGHHHHHHHH HHSSGHIEGR HMTYARAAAR QARALE+ATKA VCVLKGDGPV QGIINFEQKE SNGPVKVWGS IKGLTEGLHG FHVHEFGDNT AGCTSAGPHF NPLSRKHGGP KDEERHVGDL GNVTADKDGV ADVSIEDSVI SLSGDHCIIG RTLVVHEKAD DLGKGGNEES TKTGNAGSRL ACGVIGIAQ
Research Area Cancer
Source E.coli
Gene Names SOD1
Expression Region 2-154aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 39.9 kDa
Protein Description Full Length of Mature Protein
PubMed ID 6577438; 3160582; 3889846; 2853161; 14702039; 10830953; 15489334; 6770891; 7002610; 8528216; 8682505; 15326189; 18669648; 19608861; 20600836; 20068231; 21269460; 22496122; 22905912; 24140062; 23625804; 24275569; 1463506; 9541385; 9718300; 10329151; 129112
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Function Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Involvement in disease Amyotrophic lateral sclerosis 1 (ALS1)
Subcellular Location Cytoplasm, Mitochondrion, Nucleus
Protein Families Cu-Zn superoxide dismutase family
Database Links

HGNC: 11179

OMIM: 105400

KEGG: hsa:6647

STRING: 9606.ENSP00000270142

UniGene: Hs.443914

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