SOD1

SOD1, also known as Copper/Zinc Superoxide Dismutase (Cu/Zn SOD), is a crucial antioxidant enzyme characterized by the presence of copper and zinc ion cofactors. Functionally, SOD1 maintains the intracellular balance of reactive oxygen species by catalyzing the dismutation of superoxide anions into oxygen and hydrogen peroxide, thereby protecting cells from oxidative stress-induced damage. In terms of signaling pathways, SOD1 influences cell signaling transduction processes by regulating intracellular reactive oxygen species levels, including the activation of NF-κB, AP-1, and JAK-STAT signaling pathways, which are closely related to cell proliferation, apoptosis, and inflammatory responses. Additionally, abnormal expression of SOD1 is closely associated with the pathogenesis of neurological diseases such as Amyotrophic Lateral Sclerosis (ALS).

Popular Product:

SOD1 Recombinant Monoclonal Antibody

Validated Data

Positive WB detected in: 293 whole cell lysate, Hela whole cell lysate, Jurkat whole cell lysate, MCF-7 whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate
All lanes: SOD1 antibody at 1:1500
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 16 kDa
Observed band size: 18 kDa

FITC

Overlay histogram showing Jurkat cells stained with CSB-RA829583A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1µg/1*10⁶ cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1µg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.

The following SOD1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

SOD1 Antibodies

SOD1 Proteins

SOD1 ELISA Kits

SOD1 Antibodies

SOD1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA02864D0Rb	SOD1 Antibody, Biotin conjugated	Human	ELISA
CSB-PA02864B0Rb	SOD1 Antibody, HRP conjugated	Human	ELISA
CSB-PA022397GA01HU	SOD1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA02864C0Rb	SOD1 Antibody, FITC conjugated	Human
CSB-PA02864A0Rb	SOD1 Antibody	Human, Mouse	ELISA, WB, IHC, IF
CSB-PA004131	SOD1 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA080200	SOD1 Antibody	Human,Mouse,Rat	WB, IHC
CSB-PA238446	SOD1 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-RA829583A0HU	SOD1 Recombinant Monoclonal Antibody	Human	ELISA, WB, FC
CSB-RA022397MA1HU	SOD1 Recombinant Monoclonal Antibody	Human	ELISA, IF, FC

SOD1 Proteins

SOD1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP022397HU CSB-EP022397HU CSB-BP022397HU CSB-MP022397HU CSB-EP022397HU-B	Recombinant Human Superoxide dismutase [Cu-Zn] (SOD1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP028644h CSB-EP028644h CSB-BP028644h CSB-MP028644h CSB-EP028644h-B	Recombinant human Superoxide dismutase [Cu-Zn] protein	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP000121HU	Recombinant Human Superoxide dismutase [Cu-Zn] (SOD1) (Active)	E.Coli
CSB-AP000131HU	Recombinant Human Superoxide dismutase [Cu-Zn] protein (SOD1)	E.Coli

SOD1 ELISA Kit

SOD1 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E16845h	Human Superoxide dismutase [Cu-Zn] (SOD1) ELISA kit	serum, plasma, tissue homogenates	15.6 pg/ml

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