Recombinant Human Galectin-3 protein(LGALS3) (Active)

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Code CSB-AP000481HU
Product Type Other
Size US$84Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P17931
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Storage Buffer 0.2 ?m filtered solution in 1 × PBS, pH 7.4, 3mM DTT,lyophilized
Alias Gal-3, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by its ability to agglutinate human red blood cells is less than 10 μg/ml.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence ADNFSLHDAL SGSGNPNPQG WPGAWGNQPA GAGGYPGASY PGAYPGQAPP GAYPGQAPPG AYPGAPGAYP GAPAPGVYPG PPSGPGAYPS SGQPSATGAY PATGPYGAPA GPLIVPYNLP LPGGVVPRML ITILGTVKPN ANRIALDFQR GNDVAFHFNP RFNENNRRVI VCNTKLDNNW GREERQSVFP FESGKPFKIQ VLVEPDHFKV AVNDAHLLQY NHRVKKLNEI SKLGISGDID LTSASYTMI
Research Area Neuroscience?
Source E.Coli
Gene Names LGALS3
Expression Region 2-250aa
Tag Info Tag-Free
Mol. Weight 26.0 kDa
Protein Description Full Length of Mature Protein
PubMed ID 2261464; 2402511; 2022338; 2009535; 7682704; 9439577; 14702039; 12508121; 15489334; 8253806; 9501082; 15181153; 19594635; 19497882; 19616076; 21269460; 9582341
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Function Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus
Subcellular Location Cytoplasm, Nucleus, Secreted
Tissue Specificity A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes.
Database Links

HGNC: 6563

OMIM: 153619

KEGG: hsa:3958

STRING: 9606.ENSP00000254301

UniGene: Hs.531081

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