Your Good Partner in Biology Research
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Your Good Partner in Biology Research
| Code | CSB-RA002283A0HU |
| Size | US$350 |
| Uniprot No. | O94817 |
| Target Names | ATG12 |
| Alternative Names | Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like, ATG12, APG12, APG12L |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human ATG12 |
| Immunogen Species | Homo sapiens (Human) |
| Conjugate | Non-conjugated |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Purification Method | Affinity-chromatography |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Form | Liquid |
| Tested Applications | ELISA |
| Protocols | ELISA Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. |
| Subcellular Location | Cytoplasm, Preautophagosomal structure membrane, Peripheral membrane protein |
| Protein Families | ATG12 family |
| Tissue Specificity | Ubiquitous. |
| Database Links |
HGNC: 588 OMIM: 609608 KEGG: hsa:9140 STRING: 9606.ENSP00000425107 UniGene: Hs.264482 |
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