ATG12 Antibody

^Datasheet

Code	CSB-RA002283A0HU
Size	US$350
Uniprot No.	O94817
Immunogen	A synthesized peptide derived from human ATG12
Species Reactivity	Human
Tested Applications	ELISA
Relevance	Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.
Form	Liquid
Conjugate	Non-conjugated
Storage Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	Affinity-chromatography
Isotype	Rabbit IgG
Clonality	Monoclonal
Alias	Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like, ATG12, APG12, APG12L
Immunogen Species	Human
Protocols	ELISA Protocol
Research Area	Cell Biology
Gene Names	ATG12
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function	Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.
Subcellular Location	Cytoplasm, Preautophagosomal structure membrane, Peripheral membrane protein
Protein Families	ATG12 family
Tissue Specificity	Ubiquitous.
Database Links	HGNC: 588 OMIM: 609608 KEGG: hsa:9140 STRING: 9606.ENSP00000425107 UniGene: Hs.264482
Pathway	Autophagy NOD-like receptor signaling pathway FoxO signaling pathway

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ATG12 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL002283HU	Human Ubiquitin-like protein ATG12(ATG12) ELISA kit	serum, plasma, tissue homogenates, cell lysates	6.25 pg/mL

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