Recombinant Mouse Tumor necrosis factor receptor superfamily member 1B(Tnfrsf1b)

Code CSB-CF023978MO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P25119
Storage Buffer Tris-based buffer,50% glycerol
Species Mus musculus (Mouse)
Sequence VPAQVVLTPYKPEPGYECQISQEYYDRKAQMCCAKCPPGQYVKHFCNKTSDTVCADCEASMYTQVWNQFRTCLSCSSSCTTDQVEIRACTKQQNRVCACEAGRYCALKTHSGSCRQCMRLSKCGPGFGVASSRAPNGNVLCKACAPGTFSDTTSSTDVCRPHRICSILAIPGNASTDAVCAPESPTLSAIPRTLYVSQPEPTRSQPLDQEPGPSQTPSILTSLGSTPIIEQSTKGGISLPIGLIVGVTSLGLLMLGLVNCIILVQRKKKPSCLQRDAKVPHVPDEKSQDAVGLEQQHLLTTAPSSSSSSLESSASAGDRRAPPGGHPQARVMAEAQGFQEARASSRISDSSHGSHGTHVNVTCIVNVCSSSDHSSQCSSQASATVGDPDAKPSASPKDEQVPFSQEECPSQSPCETTETLQSHEKPLPLGVPDMGMKPSQAGWFDQIAVKVA
Source in vitro E.coli expression system
Gene Names Tnfrsf1b
Protein Names Recommended name: Tumor necrosis factor receptor superfamily member 1B Alternative name(s): Tumor necrosis factor receptor 2 Short name= TNF-R2 Tumor necrosis factor receptor type II Short name= TNF-RII Short name= TNFR-II p75 p80 TNF-a
Expression Region 23-474
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2 (By similarity).
Subcellular Location Membrane, Single-pass type I membrane protein
Database Links

KEGG: mmu:21938

STRING: 10090.ENSMUSP00000030336

UniGene: Mm.235328

Pathway TNF signaling pathway
Adipocytokine signaling pathway

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