Code | CSB-E16832m |
Size | 96T,5×96T,10×96T |
Price | Request a Quote or Start an on-line Chat |
Promotion | |
Trial Size |
24T ELISA Kit Trial Size (Only USD$150/ kit) * Sample kit cost can be deducted as a $30 credit for each 96-assay kit of the same analyte and brand you subsequently purchase in six months till depleted. Apply now |
CUSABIO's mouse CXCL13 ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse CXCL13 in serum, plasma, cell culture supernates, or tissue homogenates. This assay uses the sandwich enzyme immunoassay technique in combination with the enzyme-substrate chromogenic reaction to quantify the analyte in the sample. The color develops positively to the amount of CXCL13 in samples. The color intensity is measured at 450 nm via a microplate reader.
CXCL13 is a homeostatic chemokine that contributes to the homing and positioning of B cells and follicular helper T cells. It plays an important role in lymphoid tissue development. CXCL13 has been associated with multiple biological processes, including germinal center (GC) activity after vaccination, protective antibody production, autoimmune disease, and hematologic neoplasia. CXCL13 acts through its receptor CXCR5. Aberrant CXCL13 expression has been detected in various human diseases including rheumatoid arthritis, multiple sclerosis, Hashimoto's thyroiditis, myasthenia gravis, and chronic renal inflammation. Increased expression of CXCL13 has been detected in serum or tumor tissues in patients, which primarily functions to attract B cells and follicular B helper T cells.
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