Recombinant Mouse C-C motif chemokine 20 protein(Ccl20) (Active)

In Stock
Code CSB-AP001331MO
Product Type Chemokine
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. O89093
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias Beta-chemokine exodus-1, CC chemokine ST38, Liver and activation-regulated chemokine, Macrophage inflammatory protein 3 alpha, MIP-3-alpha
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells is in a concentration range of 0.1-10 ng/ml.
Purity >96% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM
Research Area Immunology
Source E.coli
Gene Names Ccl20
Expression Region 28-97aa
Tag Info Tag-Free
Mol. Weight 8.0 kDa
Protein Description Full Length of Mature Protein
PubMed ID 9916893; 9862452; 10064080; 11373289
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Function Acts as a ligand for C-C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions
Subcellular Location Secreted
Protein Families Intercrine beta (chemokine CC) family
Tissue Specificity Thymic medulla (at protein level). Prominently expressed in the small intestine, colon and appendix. Also found in thymus, spleen, lymph node and lung. The long form might be dominant in intestinal, and the short form in lymphoid tissues. Expressed by IL1
Database Links

KEGG: mmu:20297

STRING: 10090.ENSMUSP00000109064

UniGene: Mm.116739

Pathway Chemokine signaling pathway
TNF signaling pathway
IL-17 signaling pathway

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