Recombinant Mouse Granulocyte colony-stimulating factor protein(Csf3) (Active)

In Stock
Code CSB-AP003161MO
Product Type Colony Stimulating Factor
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P09920
Lead Time 5-10 business days
Image
Storage Buffer 0.2 m filtered 10 mM Sodium Citrate, pH 4.0, 150 mM NaCl, 0.01 % Tween?20 ,lyophilized
Alias G-CSF
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine NFS?60 cells is less than 0.05 ng/ml, corresponding to a specific activity of >2.0x107 IU/mg.
Purity >98% as determined by SDS?PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence VPLVTVSALP PSLPLPRSFL LKSLEQVRKI QASGSVLLEQ LCATYKLCHP EELVLLGHSL GIPKASLSGC SSQALQQTQC LSQLHSGLCL YQGLLQALSG ISPALAPTLD LLQLDVANFA TTIWQQMENL GVAPTVQPTQ SAMPAFTSAF QRRAGGVLAI SYLQGFLETA RLALHHLA
Research Area Immunology
Source E.coli
Gene Names Csf3
Expression Region 31-208aa
Tag Info Tag-Free
Mol. Weight 18.9 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3489940; 3494605; 3501294
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Function Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
Subcellular Location Secreted
Protein Families IL-6 superfamily
Database Links

KEGG: mmu:12985

STRING: 10090.ENSMUSP00000037762

UniGene: Mm.1238

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Hematopoietic cell lineage
IL-17 signaling pathway

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