CD47|Proteinase K|EGFR|BCMA|PD-L1|CD276|ACE2|TMPRSS2|Exosome Isolation Kits
Code | CSB-PA006562ZA01MO |
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Full Product Name | Rabbit anti-Mus musculus (Mouse) Dct Polyclonal antibody |
Uniprot No. | P29812 |
Target Names | Dct |
Alternative Names | Dct antibody; Tyrp-2 antibody; Tyrp2 antibody; L-dopachrome tautomerase antibody; DCT antibody; DT antibody; EC 5.3.3.12 antibody; DOPAchrome conversion factor antibody; DOPAchrome isomerase antibody; DOPAchrome oxidoreductase antibody; L-dopachrome Delta-isomerase antibody; SLATY locus protein antibody; Tyrosinase-related protein 2 antibody; TRP-2 antibody; TRP2 antibody |
Raised in | Rabbit |
Species Reactivity | Mus musculus |
Immunogen | Recombinant Mouse L-dopachrome tautomerase (Dct), partial (24-472AA) |
Immunogen Species | Mus musculus (Mouse) |
Conjugate | Non-conjugated |
Clonality | Polyclonal |
Isotype | IgG |
Purification Method | Protein A/G |
Concentration | It differs from different batches. Please contact us to confirm it. |
Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Form | Liquid |
Tested Applications | ELISA, WB (ensure identification of antigen) |
Protocols | ELISA Protocol |
Troubleshooting and FAQs | Antibody FAQs |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Lead Time | Made-to-order |
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Function | Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA) |
Gene References into Functions |
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Involvement in disease | The slaty mutation in Tyrp2 leads to a decrease of DT activity and a consequent change in the pigmentation of the mice to a dark gray/brown eumelanin. The slaty-2j mutation has a similar phenotype, the slaty-lt (light) mutation has a more severe effect and is semidominant; its phenotype may be a result of the failure of the enzyme to be correctly targeted to its normal location on the inner face of the melanosomal membrane. |
Subcellular Location | Melanosome membrane, Single-pass type I membrane protein, Melanosome |
Protein Families | Tyrosinase family |
Tissue Specificity | Melanocytes and retinal pigmented epithelium. |
Database Links |
KEGG: mmu:13190 STRING: 10090.ENSMUSP00000022725 UniGene: Mm.19987 |
Tel: 301-363-4651
Email: support@cusabio.com
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