Recombinant Human Interleukin-17F protein(IL17F) (Active)

Code CSB-AP001841HU
Product Type Interleukin
Size Pls inquiry other sizesPurchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q96PD4
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias IL-17F
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 20 ng/ml, corresponding to a specific activity of >5.0x104 IU/mg.
Purity >95% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence M+RKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ
Research Area Immunology
Source E.Coli
Gene Names IL17F
Expression Region 31-163aa
Product Info Tag-Free
Mol. Weight 30.1 kDa
Protein Description Full Length of Mature Protein
PubMed ID 11591732; 14574404; 15489334; 11591768; 15340161; 11574464; 19838198; 21350122
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Function Ligand for IL17RA and IL17RC
Involvement in disease Candidiasis, familial, 6 (CANDF6)
Subcellular Location Secreted
Protein Families IL-17 family
Tissue Specificity Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.
Database Links

HGNC: 16404

OMIM: 606496

KEGG: hsa:112744

STRING: 9606.ENSP00000337432

UniGene: Hs.272295

Pathway IL-17 signaling pathway
Th17 cell differentiation

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