IL17F Antibody, Biotin conjugated

Datasheet
Code CSB-PA842733LD01HU
Size US$299
Uniprot No. Q96PD4
Protocols ELISA Protocol
Immunogen Recombinant Human Interleukin-17F protein (31-163AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover (PubMed:11591732, PubMed:11591768, PubMed:11574464). Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (PubMed:11591732). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation (By similarity).
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Interleukin-17F (IL-17F) (Cytokine ML-1), IL17F
Immunogen Species Homo sapiens (Human)
Research Area Cardiovascular
Target Names IL17F
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Ligand for IL17RA and IL17RC
Involvement in disease Candidiasis, familial, 6 (CANDF6)
Subcellular Location Secreted
Protein Families IL-17 family
Tissue Specificity Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.
Database Links

HGNC: 16404

OMIM: 606496

KEGG: hsa:112744

STRING: 9606.ENSP00000337432

UniGene: Hs.272295

Pathway IL-17 signaling pathway
Th17 cell differentiation

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