Code | CSB-RA263943A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IF | 1:20-1:200 |
HIF1A is known to be associated with the upregulation of hypoxia-inducible genes such as phosphoglycerate kinase (PGK) and lactate dehydrogenase A (LDHA), both of which function to metabolically adapt the tissue to oxygen deprivation and anaerobic ATP synthesis. Previous studies of HIF1A deficient mice have indicated that HIF1A is essential for early vascular development during the embryonic stage. HIF1A increases inducible NO synthase levels, which dampens ischemic injury. A study shows that HIF1A is necessary for the myocardium to adapt to pressure overload and increase angiogenesis.
The production of this recombinant HIF1A antibody started with immunization. And then the workflow included B cell harvest and enrichment; import single B cell; assays to identify the specificity, affinity & functionality of the cell; export the single B cell; cDNA synthesis and sequencing; express the HIF1A antibody in mammalian cells. The target HIF1A antibody was validated in ELISA, IF.Applications : Immunohistochemistry
Sample type: serum
Review: Western blot and IHC assays were conducted to demonstrate the efects between PESV treatment and circ_0016760 on HIF1A protein expression in vivo.
By Anonymous