Toxin A (Tosatoxumab Biosimilar) Recombinant Monoclonal Antibody

Code CSB-RA357716MA1FKZ
Size US$199
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Product Details

Uniprot No.
Target Names
Staphylococcus aureus Toxin A
Alternative Names
Alpha-hemolysin antibody; Alpha-HL antibody; Alpha-toxin antibody; hly antibody; hla antibody; Toxin A antibody; Tosatoxumab
Species Reactivity
Staphylococcus aureus
Immunogen
Recombinant Staphylococcus aureus Toxin A protein
Immunogen Species
Staphylococcus aureus
Conjugate
Non-conjugated
Clonality
Monoclonal
Isotype
Human IgG1 kappa
Purification Method
Affinity-chromatography
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, FACS
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.
Recommended Service
High throughput recombinant antibody production to help select the right therapeutic antibodies at competitive prices.

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Target Background

Function
Alpha-toxin binds to the membrane of eukaryotic cells (particularly red blood cells, RBC) forming pores, resulting in hemolysis, with the release of low-molecular weight molecules leading to eventual osmotic RBC lysis. Human RBCs bind much less alpha-toxin than do rabbit RBCs. Heptamer oligomerization and pore formation is required for lytic activity.
Subcellular Location
Secreted.
Protein Families
Aerolysin family
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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