ADAP2 Antibody

Datasheet

Code	CSB-PA889071LA01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ADAP2 Polyclonal antibody

Uniprot No.

Q9NPF8

Target Names

ADAP2

Alternative Names

Adap2 antibody; ADAP2_HUMAN antibody; Arf-GAP with dual PH domain-containing protein 2 antibody; ArfGAP with dual PH domains 2 antibody; cent b antibody; Centa 2 antibody; CENTA2 antibody; Centaurin alpha 2 antibody; Centaurin alpha 2 protein antibody; Centaurin beta antibody; Centaurin-alpha-2 antibody; Cnt-a2 antibody; HSA272195 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Arf-GAP with dual PH domain-containing protein 2 protein (110-381AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ADAP2 Antibody (Product code: CSB-PA889071LA01HU) is Non-conjugated. For ADAP2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA889071LB01HU	ADAP2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA889071LC01HU	ADAP2 Antibody, FITC conjugated
Biotin	CSB-PA889071LD01HU	ADAP2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Possesses a stoichiometry of two binding sites for InsP4 with identical affinity.

Gene References into Functions

ArfGAP domain-containing protein 2 (ADAP2) is identified as a key novel scaffolding protein that integrates different modules of the RIG-I pathway, located at distinct subcellular locations, and mediates cellular antiviral type I interferon production. PMID: 27956705
Data suggest ADAP2 (an interferon-beta stimulated gene) disrupts pathogenic internalization of some RNA viruses/virions (dengue, vesicular stomatitis) by altering ADP ribosylation factor 6-mediated processes including up-regulation of pinocytosis. PMID: 26372645
Centaurin-alpha interacts with beta-tubulin and stabilizes microtubules. PMID: 23285209
The human gene for centaurin alpha 2 is located on chromosome 17, position 17q11.2, near the neurofibromatosis 1 (NF1) locus and concentrated at the plasma membrane. PMID: 14690521

Subcellular Location

Cytoplasm. Cell membrane. Note=Constitutively associated with the plasma membrane. Excluded from the nucleus.

Tissue Specificity

Highly expressed in placenta, spleen, kidney, skeletal muscle and adrenal gland. Weakly expressed in thyroid, liver, heart, lung, small intestine, peripheral blood leukocytes. Not detected in spinal cord, brain, stomach, trachea, colon, lymph node and bon

Database Links

HGNC: 16487

OMIM: 608635

KEGG: hsa:55803

STRING: 9606.ENSP00000329468

UniGene: Hs.514063

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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