CDK2AP2 Antibody

Code CSB-PA005063LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA005063LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CDK2AP2 Polyclonal antibody
Uniprot No.
Target Names
CDK2AP2
Alternative Names
CDK2AP2 antibody; DOC1RCyclin-dependent kinase 2-associated protein 2 antibody; CDK2-associated protein 2 antibody; DOC-1-related protein antibody; DOC-1R antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cyclin-dependent kinase 2-associated protein 2 protein (1-126AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CDK2AP2 Antibody (Product code: CSB-PA005063LA01HU) is Non-conjugated. For CDK2AP2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA005063LB01HU CDK2AP2 Antibody, HRP conjugated ELISA
FITC CSB-PA005063LC01HU CDK2AP2 Antibody, FITC conjugated
Biotin CSB-PA005063LD01HU CDK2AP2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A.
Gene References into Functions
  1. Our findings suggest that alteration of p16, p14, p27, p21, and p53 status may contribute to carcinogenesis and the clinical behavior of HPV-negative adenocarcinoma of the uterine cervix PMID: 25675191
  2. antitumor effects of DOC-1R may be mediated by negatively regulating G1 phase progression and G1/S transition through inhibiting CDK2 expression and activation PMID: 23781148
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
CDK2AP family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 30833

KEGG: hsa:10263

STRING: 9606.ENSP00000301488

UniGene: Hs.523835

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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