CEP41 Antibody

Datasheet

Code	CSB-PA080028
Size	US$119
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9BYV8

Target Names

CEP41

Alternative Names

centrosomal protein 41 kDa antibody; Centrosomal protein of 41 kDa antibody; CEP 41 antibody; Cep41 antibody; CEP41_HUMAN antibody; testis specific 14 antibody; testis specific gene A14 antibody; Testis specific gene A14 protein antibody; testis specific protein A14 antibody; Testis-specific gene A14 protein antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human CEP41.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
IHC	1:100-1:300
ELISA	1:40000

Protocols

Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium.

Gene References into Functions

In cortices, the MEST promoter was hemimethylated, as expected for a differentially methylated imprinting control region, whereas the COPG2 and TSGA14 promoters were completely demethylated, typical for transcriptionally active non-imprinted genes. PMID: 22456293
The data identified CEP41 mutations as a cause of Joubert syndrome and implicated tubulin post-translational modification in the pathogenesis of human ciliary dysfunction. PMID: 22246503
Three rare potentially pathogenic variants were identified in the TSGA14 gene, which encodes a centrosomal protein. PMID: 21438139

Involvement in disease

Joubert syndrome 15 (JBTS15)

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes mainly to the cilium basal body and in primary cilia.

Protein Families

CEP41 family

Tissue Specificity

[Isoform 1]: Expressed in testis and fetal tissues.; [Isoform 3]: Expressed in testis and fetal tissues.

Database Links

HGNC: 12370

OMIM: 610523

KEGG: hsa:95681

STRING: 9606.ENSP00000223208

UniGene: Hs.368315

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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