CHIC2 Antibody

Code CSB-PA892453ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human bladder cancer using CSB-PA892453ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CHIC2 Polyclonal antibody
Uniprot No.
Target Names
CHIC2
Alternative Names
BrX-like translocated in leukemia antibody; BTL antibody; Chic2 antibody; CHIC2_HUMAN antibody; Cystein-rich hydrophobic domain 2 antibody; Cysteine-rich hydrophobic domain 2 protein antibody; MGC21173 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cysteine-rich hydrophobic domain-containing protein 2 protein (1-165AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Gene References into Functions
  1. used fluorescence in situ hybridization to detect deletion of the CHIC2 locus at 4q12 as a surrogate for the FIP1L1-PDGFRA fusion and was observed in bone marrow cells for 3 of 5 patients with systemic mast cell disease associated with eosinophilia PMID: 12842979
  2. studied a new FISH method to detect CHIC2 deletion, FIP1L1/PDGFRA fusion and PDGFRA translocation in patients with myeloid neoplasms associated with eosinophilia PMID: 19118897
Involvement in disease
A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4;12)(q12;p13) with ETV6.
Subcellular Location
Cell membrane. Cytoplasmic vesicle. Note=Also present at a Golgi-like vesicular compartment and at scattered vesicles.
Protein Families
CHIC family
Database Links

HGNC: 1935

OMIM: 604332

KEGG: hsa:26511

STRING: 9606.ENSP00000263921

UniGene: Hs.335393

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