NPAP1 Antibody

Code CSB-PA284200
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA284200(NPAP1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA284200(NPAP1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
NPAP1
Alternative Names
NPAP1 antibody; C15orf2Nuclear pore-associated protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human NPAP1
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May be involved in spermatogenesis.
Gene References into Functions
  1. NPAP1 is specific to primate species and absent from the 15q11q13-orthologous regions in all nonprimate mammals. PMID: 24482533
  2. C15orf2 is part of the nuclear pore complex or its associated molecular networks. PMID: 22694955
  3. C15orf2 gene is imprinted, with monoallelic expression from the paternal allele in fetal brain. PMID: 17337158
  4. These results indicate that C15orf2 might have an important role in human biology and that a deficiency of C15orf2 might contribute to Prader-Willi syndrome. PMID: 20020165
  5. The results from this study show an involvement of microdeletions at 15q11.2 that predispose patients to idiopathic generalized epilepsies. PMID: 19843651

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Subcellular Location
Nucleus, nucleoplasm. Nucleus inner membrane. Note=Colocalizes with the NPC and nuclear lamins at the nuclear periphery.
Tissue Specificity
Testis-specific in adults. In fetal brain expressed only from the paternal allele.
Database Links

HGNC: 1190

OMIM: 610922

KEGG: hsa:23742

STRING: 9606.ENSP00000333735

UniGene: Hs.649663

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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