Code | CSB-AP000941HU |
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Size | $142 |
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Our recombinant human CCL21 protein, expressed in E. coli, encompasses the full-length mature protein sequence, spanning from amino acids 24 to 134. This tag-free protein is supplied as a lyophilized powder that can be easily reconstituted with sterile water or buffer. The purity of our recombinant CCL21 is >97%, as confirmed by SDS-PAGE and HPLC analysis, while the endotoxin content remains below 1.0 EU/µg, as determined using the LAL method. The protein demonstrates full biological activity, as shown in a chemotaxis bioassay with human lymphocytes, eliciting activity in a concentration range of 10-100 ng/ml.
As a member of the CC chemokine family, C-C motif chemokine 21 (CCL21) has a significant impact on immune cell migration and function. Comprehensive insights into CCL21's functions and mechanisms are crucial to understanding its role within the immune system and its potential as a therapeutic target for immune-related diseases.
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