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| Code | CSB-AP001341MO |
| Product Type | Chemokine |
| Size |
US$112Purchase it in Cusabio online store (only available for customers from the US) |
| Uniprot No. | P86793 |
| Lead Time | 5-10 business days |
| Image | |
| Storage Buffer | 0.2 μm filtered PBS, pH 7.4 ,lyophilized |
| Alias | 6Ckine, Small-inducible cytokine A21c, Thymus-derived chemotactic agent 4, TCA4 |
| Species | Mus musculus (Mouse) |
| Biological_Activity | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine T-lymphocytes is in a concentration range of 10-100 ng/ml. |
| Purity | >97% as determined by SDS-PAGE and HPLC. |
| Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
| Sequence | SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG |
| Research Area | Immunology |
| Source | E.coli |
| Gene Names | Ccl21c |
| Expression Region | 24-133aa |
| Tag Info | Tag-Free |
| Mol. Weight | 12.1 kDa |
| Protein Description | Full Length of Mature Protein |
| PubMed ID | 11123313; 19468303; 15489334; 9419363 |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. |
| Subcellular Location | Secreted |
| Protein Families | Intercrine beta (chemokine CC) family |
| Tissue Specificity | Expressed strongly in lung, spleen, thymus, peripheral and mesentric lymph nodes. Also expressed in the testis, kidney, liver, and heart. |
| Database Links |
KEGG: mmu:100041504 UniGene: Mm.407493 |
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