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Code | CSB-AP001341MO |
Size |
$2617Purchase it in Cusabio online store (only available for customers from the US) |
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Purity | >97% as determined by SDS-PAGE and HPLC. |
Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
Activity | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine T-lymphocytes is in a concentration range of 10-100 ng/ml. |
Target Names | Ccl21c |
Uniprot No. | P86793 |
Research Area | Immunology |
Alternative Names | Ccl21c; Scya21cC-C motif chemokine 21c; 6Ckine; Beta-chemokine exodus-2; Small-inducible cytokine A21c; Thymus-derived chemotactic agent 4; TCA4 |
Species | Mus musculus (Mouse) |
Source | E.coli |
Expression Region | 24-133aa |
Complete Sequence | SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG |
Mol. Weight | 12.1 kDa |
Protein Length | Full Length of Mature Protein |
Tag Info |
Tag-Free |
Form | Lyophilized powder |
Buffer | Lyophilized from a 0.2 µm filtered PBS, pH 7.4 |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Troubleshooting and FAQs |
Protein FAQs |
Storage Condition | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Shelf Life | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
Lead Time | 5-10 business days |
Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Datasheet & COA | Please contact us to get it. |
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Function |
Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs.
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Subcellular Location | Secreted. |
Protein Families | Intercrine beta (chemokine CC) family |
Tissue Specificity | Expressed strongly in lung, spleen, thymus, peripheral and mesentric lymph nodes. Also expressed in the testis, kidney, liver, and heart. |
Database Links |
KEGG: mmu:100041504 UniGene: Mm.407493 |