Abd-B Antibody

1. analysis of blocking and bypass activities of the Fab-8 boundary in the Drosophila bithorax complex PMID: 27428541
2. Abd-B is required in neurons during development for females to become highly receptive to male courtship. Abd-B neurons control pausing, a key aspect of female sexual receptivity, in response to male courtship. PMID: 24998527
3. ABD-B binds more strongly to oligonucleotides containing two 5'-TTAT-3' canonical core motifs than the probe containing the 5'-TTAC-3' motif. PMID: 24219869
4. Abd-B provides cues for integrin localization, critical for stem cell positioning. PMID: 24480643
5. We also found that Abd-B expression in the secondary cells contributes to glycosylation of at least three accessory gland proteins: ovulin (Acp26Aa), CG1656, and CG1652 PMID: 23555301
6. By functionally dissecting the Abd-B protein, new features of Abd-B dependent target gene regulation were detected. PMID: 22005458
7. The promoter targeting sequences (PTS) from Abd-B locus overcome the enhancer blocking effect of insulators and facilitate long-range enhancer-promoter interactions in transgenic flies PMID: 20045684
8. Studies indicate that interaction of Abdominal-B (ABD-B) with dorso ventral and intrasegmental positional information leads to the local activation of ABD-B primary targets in the dorsal region of the eighth abdominal segment (A8). PMID: 19247941
9. The analysis of these mutations has allowed us to define a new infraabdominal-8 regulatory region, located 5' to the Abdominal-B transcription unit, and has helped to characterize better the complex regulation of the Abdominal-B gene. PMID: 12399311
10. The promoter targeting sequence (PTS) from the Abdominal-B locus of the bithorax complex facilitates the activity of a distantly located enhancer in transgenic embryos and it restricts the enhancer to a single promoter. PMID: 12490558
11. the Fab-7 boundary contains separable regions that function at different stages of development PMID: 15329342
12. Abd-B acts at multiple levels to regulate gonad development and is a conserved factor in establishing gonad sexual dimorphism in diverse species. PMID: 15454263
13. certain mutations in Abd-B can be rescued in trans by the other copy of the gene in the genetic phenomenon known as transvection PMID: 15572134
14. Abdominal-B Hox protein directly activates expression of the yellow pigmentation gene in posterior segments PMID: 16814723
15. Regulatory regons seems to control specifically the level of Abd-B expression in only one parasegment of the bithorax. PMID: 16818450
16. Abdominal-B induces the expression of four intermediate signaling molecules and transcription factors; this expression results in the mosaic activation of several realizator genes during the organogenesis of the external respiratory organ of the larva. PMID: 17113384
17. Enhancer interference limits the interaction of the Abdominal-B promoter to the enhancer(s) from only one regulatory domain in a specific abdominal segment. PMID: 17307884
18. the enhancer blocking capability of the Fab-8 insulator in stably transfected Drosophila S2 cells and show this activity depends on the Fab-8 CTCF binding sites PMID: 17825318
19. Fab-7 and Fab-8 boundaries effectively interact with the upstream region of the Abd-B promoter PMID: 18426914
20. development of the dorsal histoblast nests that will give rise to the adult epithelium is impaired in the posterior segments which identity is specified by Abdominal-B PMID: 18667003
21. Using gene conversion, we exchanged the Fab-7 and Fab-8 boundaries within the BX-C. PMID: 18987027

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KEGG: dme:Dmel_CG11648

STRING: 7227.FBpp0082826

UniGene: Dm.1763