CadN Antibody

1. This is the first in vivo evidence for N-cadherin negatively and cell autonomously controlling collective migration. PMID: 25593128
2. Study demonstrates that the classical cadherin, N-cadherin, and an atypical cadherin, Flamingo, act redundantly to instruct the targeting choices made by every photoreceptor axon. PMID: 23870124
3. switching of CadN expression during neuronal differentiation involves regulated cation influx within neurons PMID: 22542600
4. Results suggest that N-cadherin is regulated in a Schizo/Loner- and d-Arf1-dependent manner. PMID: 22595515
5. These results suggest that, unlike their vertebrate counterparts, invertebrate cadherins may utilize multiple extracellular cadherin domains to form intercellular adhesive bonds. PMID: 22171007
6. Data demonstrate that N-cadherin, DLAR, and Liprin-alpha function in a complex to regulate adhesive interactions between pre- and post-synaptic cells and provide a novel mechanism for controlling the activity of Liprin-alpha in the developing growth cone. PMID: 19766621
7. DN-cadherin is required for spatial arrangement of nerve terminals and ultrastructural organization of synapses. PMID: 11906210
8. N-cadherin mediates dendro-dendritic interactions between PNs and thus contributes to refinement of PN dendrites to single glomeruli. PMID: 15066265
9. This study propose N-cad, a homophilic cell adhesion molecule, acts in a permissive fashion to promote subclass-specific sorting of ORN axon terminals into protoglomeruli. PMID: 15066266
10. N-cadherin has a role in the first stage of the two-stage layer-selection process of R7 photoreceptor afferents PMID: 15673571
11. During the first half of pupal development, N-cadherin is required for R7 photoreceptor neurons growth cones to terminate within a temporary target layer in the medulla PMID: 16123134
12. DN-cadherins integrate input from at least two signaling pathways, resulting in a coordinated cell movement PMID: 16887833
13. CadN alternative splicing might provide a novel mechanism to fine-tune its adhesive activity at different developmental stages or to restrict the use of high-affinity 18b-type isoforms at the adult stage. PMID: 16914742
14. CadN mediates homophilic adhesive interactions between R7 growth cones and medulla neurons to regulate layer-specific target selection. PMID: 17320070
15. N-cadherin expression on one growth cone in a specific layer is essential for targeting of processes of another neuron to this layer. PMID: 18400161
16. N-Cadherin gene maintained three sets of mutually-exclusive alternatively-spliced exons for over 400 million years. PMID: 19343204

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KEGG: dme:Dmel_CG7100

STRING: 7227.FBpp0099721

UniGene: Dm.5768