Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) COR15A Polyclonal antibody

Uniprot No.

Q42512

Target Names

COR15A

Alternative Names

COR15A antibody; At2g42540 antibody; F14N22.19Protein COLD-REGULATED 15A antibody; chloroplastic antibody; AtCOR15A antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana COR15A protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Target Background

Function

Exhibits cryoprotective activity toward stromal substrates (e.g. LDH and rubisco) in chloroplasts and in protoplasts and confers freezing tolerance to plants in a CBF-dependent manner. Protectant against various stresses (e.g. cold, drought and heat stress) by preventing protein aggregation (e.g. LDH) and attenuating enzyme inactivation. Influences the intrinsic curvature of the inner membrane of the chloroplast envelope, and modulates the freeze-induced lamellar-to-hexagonal II phase transitions that occur in regions where the plasma membrane is brought into close apposition with the chloroplast envelope during freeze-induced osmotic contraction. Mediates a shift in the melting curves of phospholipids-containing membranes to lower temperatures. Involved in the regulation of leaf senescence by abscisic acid (ABA) in a VNI2-dependent manner.

Gene References into Functions

COR15A-membrane interaction PMID: 28793212
we have extended these investigations to two related proteins, LEA11 and LEA25. LEA25 is much longer than LEA11 and COR15A, but shares a conserved central sequence domain with the other two proteins. The C- and N-terminal extensions of LEA25 were important in cryoprotection, as the central domain itself (2H, 4H) only provided a low level of protection. PMID: 28109185
GT-4 interacts with TEM2 and then co-regulates the salt responsive gene Cor15A to improve salt stress tolerance. PMID: 25465615
The results showed that the expression of the exogenous AtCBF3 and AtCOR15A could promote the cold adaptation process to protect eggplant plants from chilling stress. PMID: 25103420
COR15A encodes a small, plastid-targeted polypeptide that is processed to a mature form called Cor15am which localizes almost exclusively to the chloroplast stroma. PMID: 17384167
indicate that Cor15am functions as a protectant against various stresses by preventing protein aggregation PMID: 18540080
Data show that increase in expression expression of the cold response genes, COR15A, RD29A, and CBF3, resulting in enhanced tolerance to freezing temperatures. PMID: 19363684
Trimethylation of histone H3 at lysine 27 decreases at COR15A and ATGOLS3 during cold-induced transcription. PMID: 19500304
Cooling induction of COR15a is mediated by the CRT/DRE element and the CBF genes. PMID: 19563440

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Subcellular Location

Plastid, chloroplast stroma.

Protein Families

COR15 protein family

Database Links

KEGG: ath:AT2G42540

STRING: 3702.AT2G42540.2

UniGene: At.20845

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COR15A Antibody

Product Details

Customer Reviews and Q&A

Target Background