EDS1 Antibody

1. EDS1 with PAD4, besides promoting SA biosynthesis, maintains important salicylic acid (SA)-related resistance programs, thereby increasing robustness of the innate immune system. PMID: 27861989
2. Data indicate that Arabidopsis proteins PAD4, LSD1 and EDS1 constitute a molecular hub, which integrates plant responses to water stress, vegetative biomass production and generative development. PMID: 26754794
3. LSD1 and EDS1 regulate processes extinguishing excessive energy, reactive oxygen species formation and subsequent programmed cell death in response to different stresses related to impaired electron transport. PMID: 24471507
4. EDS1 influences the accumulation rate of immune-related lipid peroxidation precursors or products. PMID: 25114016
5. the constitutive defence phenotypes of constitutive induced resistance 1 mutant require both EDS1 and PAD4, indicating that CIR1 lies upstream of the EDS1-PAD4 regulatory node in the immune signalling network. PMID: 25303634
6. Mutational analysis of the EDS1-SAG101 heterodimer and a derived EDS1-PAD4 structural model shows that EDS1 signals within mutually exclusive heterocomplexes. PMID: 24331460
7. A map-based cloning analysis revealed that CHS1 encodes a TIR-NB-type protein. The chilling sensitivity of chs1 was fully rescued by pad4 and eds1, but not by ndr1. PMID: 23651299
8. EDS1 is a positive regulator of nonhost resistance against E. amylovora in A. thaliana. PMID: 22316300
9. Data show that the salicylic acid (SA) or infection-induced suppression requires an enhanced desease resistance1 (EDS1) and nonexpressor of pathogenesis-related genes1 (NPR1)-dependent SA pathway in conjunction with Plasmodesmata-located protein5 (PDLP5). PMID: 23749844
10. Genetic analyses identified salicylic acid biosynthesis and EDS1 signaling as well as biosynthesis of the indole-glucosinolate 4MI3G as essential components required for loss-of-WRKY18 WRKY40-mediated resistance towards Golovinomyces orontii. PMID: 23617415
11. LSD1, EDS1, and PAD4 participate in the regulation of various molecular and physiological processes that influence Arabidopsis fitness. PMID: 23400705
12. EDS1 and PAD4, both central regulators of basal resistance and effector-triggered immunity, as well as HSP90 chaperones and their cochaperones RAR1 and SGT1B, are required for the DFPM-induced root growth arrest. PMID: 23275581
13. results suggest that EDS1, PAD4, SAG101 function independently as well as in a ternary complex to mediate plant defense signaling PMID: 22072959
14. EDS1 molecularly connects TIR-NB-LRR disease resistance protein RPS4 recognition of bacterial effector AvrRps4 to defense pathways; EDS1 behaves as an effector target and activated TIR-NB-LRR signal transducer for defense across cell compartments PMID: 22158818
15. study shows EDS1 forms complexes with the TIR-NB-LRR resistance proteins RPS4 and RPS6 and the negative immune regulator SRFR1 at a cytoplasmic membrane PMID: 22158819
16. An EDS1-PAD4 complex is necessary for basal resistance involving transcriptional up-regulation of PAD4 itself and mobilization of salicylic acid defenses. PMID: 21434927
17. Arabidopsis protein, EDS1, is an important regulator of innate immunity. PMID: 21301097
18. EDS1 regulates the response of the plant to chloroplast-derived O2*- by promoting salicylic acid-assisted accumulation of H2O2 as part of a mechanism restricting cell death. PMID: 20163553
19. Differential susceptibility to PM is correlated with differences in EDS1 expression PMID: 20145949
20. ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1) and its interacting partner, PHYTOALEXIN DEFICIENT 4 (PAD4), constitute a regulatory hub that is essential for basal resistance to invasive biotrophic and hemi-biotrophic pathogens. PMID: 15939664
21. Data show that EDS1 interacts in vivo with another protein, SENESCENCE-ASSOCIATED GENE101 (SAG101), and that interactions of EDS1 and its signaling partners are important for plant defense signal relay. PMID: 16040633
22. There are salicylic-independent functions of FMO1 and NUDT7 in EDS1-conditioned disease resistance and cell death. PMID: 16531493
23. Singlet oxygen activates a complex stress-response program with EDS1 playing a key role in initiating and modulating several of its steps. PMID: 16790029
24. The susceptibility of A. thaliana plants to Alternaria brassicicola that induces defensive pathways via EDS1 and PAD4 is reported. PMID: 16813576
25. A PHYTOALEXIN DEFICIENT4 (PAD4) mode of action that is uncoupled from EDS1 (ENHANCED DISEASE SUSCEPTIBILITY1) determines the extent of aphid feeding in the phloem. PMID: 17725549
26. EDS1 is partially required for Pseudomonas syringae HopW1-1-induced disease resistance. PMID: 18266921
27. Data suggest that the balanced activities of LSD1, EDS1, PAD4, and EIN2 regulate signaling of programmed cell death, light acclimation, and holistic defense responses that are initiated, at least in part, by redox changes of the plastoquinone pool. PMID: 18790826
28. EDS1 and salicylic acid act redundantly to regulate disease resistance. PMID: 19578402
29. Analysis shows that nuclear accumulation of snc1 and the defense signaling components Enhanced Disease Susceptibility 1 and Nonexpresser of PR genes 1 is significantly reduced in mos7-1 plants, while nuclear retention of other proteins is unaffected. PMID: 19700630

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KEGG: ath:AT3G48090

STRING: 3702.AT3G48090.1

UniGene: At.3138