Fas2 Antibody

1. Fas2-mediated intermicrovillar homophilic adhesion complexes help stabilize the brush border. PMID: 27072072
2. Csk and its SFK substrates impinge upon homeostatic control of NMJ function by regulating downstream expression or localization of FasII. PMID: 26901416
3. Fas 2 is linked to core clock by Mef2 and influences circadian cycle within pacemaker neurons; Mef2 is required for this daily fasciculation-defasciculation cycle PMID: 23889933
4. the expression of Adf-1 targets Staufen and Fasciclin II (FasII), identified through larval brain ChIP-Seq for Adf-1, is negatively regulated by Adf-1, and manipulations of these genes predictably modify dendrite growth. PMID: 23864680
5. Together with our results suggesting that DmRet and DmGfrl do not function in cis in Drosophila, which lacks GDNF ligands, these data imply that DmGfrl may be an evolutionarily ancient binding partner for NCAM/FasII. PMID: 23284846
6. The inability of Tao mutant cells to shorten their membranes is caused by the accumulation of the cell adhesion molecule Fasciclin 2. PMID: 23266957
7. this FasII isoform has unique functions in synaptic development independent of transsynaptic adhesion. beag and dsmu1 mutants demonstrate an essential role for these previously uncharacterized splicing factors in the regulation of synapse development PMID: 22593074
8. integrins act through CaMKII activation to control the localization of Fasciclin 2 in the development of NMJ synaptic morphology PMID: 12091308
9. Fas2(spin) rotation defects are linked to an abnormal endocrine function and an elevated level of juvenile hormone. PMID: 12702654
10. Data show that fasciclin 2 directs cluster asymmetry essential for timing delamination of epithelial cells from the epithelium in preparation for migration. PMID: 15056617
11. Drosophila larval neuromuscular junction to investigate the pathways activated by Fasciclin II (FasII) PMID: 15976083
12. Fas II functions to restrict branch length and arbor expanse during development of innervation to the Dorsal Longitudinal (flight) Muscle PMID: 16055111
13. Fas2 mediates trans-synaptic adhesion, which contributes to postsynaptic molecular assembly at the onset of synaptogenesis. PMID: 18070911
14. Loss of fas2 interacts with genetic conditions that perturb EGFR signalling. Fas2 is expressed in patterns during imaginal disc development, and in eye we have shown that this depends on EGFR activity, implying participation in a negative-feedback loop. PMID: 19141676

Show More

Hide All

KEGG: dme:Dmel_CG3665

STRING: 7227.FBpp0070633

UniGene: Dm.1687