FTSH4 Antibody

Code CSB-PA529299XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FTSH4 Polyclonal antibody
Uniprot No.
Target Names
FTSH4
Alternative Names
FTSH4; At2g26140; T19L18.5; ATP-dependent zinc metalloprotease FTSH 4, mitochondrial; AtFTSH4
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana FTSH4 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Probable ATP-dependent zinc metallopeptidase. Involved in the assembly and/or stability of the complex V of the mitochondrial oxidative phosphorylation system.
Gene References into Functions
  1. Growth arrest in the ftsh4-1 mutant is caused by cell cycle dysregulation in addition to the loss of stem cell identity. PMID: 29538317
  2. Data revealed several putative targets of FTSH4, novel (mitochondrial pyruvate carrier 4 (MPC4) and Pam18-2) and known (Tim17-2) substrates of this protease. Furthermore, These results demonstrate that FTSH4 degrades damaged proteins by oxidative stress in mitochondria and provide new insights into the function of FTSH4 in the maintenance of plant mitochondrial proteome. PMID: 29156584
  3. Maintaining mitochondria functionality within the The shoot apical meristem, dependent on AtFTSH4, is vital to preserving stem cell activity throughout development PMID: 27321362
  4. Loss of function of transcription factor WRKY75 in the mitochondrial protease ftsh4-4 mutants decreased the levels of salicylic acid (SA) and reversed the senescence phenotype. PMID: 28250067
  5. the loss of FtsH4 regulates development and architecture by mediating the peroxidase-dependent interplay between hydrogen peroxide and auxin homeostasis PMID: 25763704
  6. mitochondrial FtSH4 gene-mediated peroxidase accumulation regulates arabidopsis architecture PMID: 24482432
  7. processing of AtFtsH4 precursor by mitochondrial processing peptidase PMID: 22986791
  8. AtFtsH4 is an exclusively mitochondrial protein while AtFtsH11 is found in both chloroplasts and mitochondria. PMID: 16247555
  9. Lack of AtFtsH4 results in impairment of organelle development and Arabidopsis leaf morphology under short-day conditions. PMID: 19453455

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Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.
Protein Families
AAA ATPase family; Peptidase M41 family
Database Links

KEGG: ath:AT2G26140

STRING: 3702.AT2G26140.1

UniGene: At.23415

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