HEN1 Antibody

1. we show HESO1 may also act redundantly with URT1 in miRNA uridylation when HEN1 is fully competent PMID: 25928341
2. Light-activated HEN1 expression depended on the photoreceptors phytochrome A (phyA), phyB, cryptochrome 1 (cry1), and cry2 and key transcriptional regulators ELONGATED HYPOCOTYL5 (HY5) and HY5-HOMOLOG. PMID: 25052717
3. Data suggest a mechanism of plant miRNA maturation which involves binding of the HEN1 methyltransferase to the DICER-LIKE 1 ribonuclease DCL1*RNA-binding protein HYL1*miRNA complex. PMID: 25680966
4. Data indicate that the ago1 mutation in hen1 suppressed micriRNA 3' modifications. PMID: 23839787
5. AGO1, HYL1, and HEN1 function in proximal-distal and vascular patterning of leaves. PMID: 22623415
6. Motif mapping analysis revealed that the amino acids located between positions 139 and 320 of Zucchini yellow mosaic virus HC-Pro were associated with Arabidopsis HEN1 interaction. PMID: 21593273
7. A mutation in RNA-dependent RNA polymerase 2 rescued the defects in miRNA methylation of hen1-2, revealing a previously unsuspected, negative influence of siRNAs on HEN1-mediated miRNA methylation. PMID: 20448024
8. Kinetic parameters with natural RNA substrates show that HEN1 is highly catalytically efficient in the absence of supplementary proteins. The enzyme modifies individual strands in succession leading to complete methylation of an RNA duplex. PMID: 20705645
9. HEN1 is a miRNA methyltransferase that adds a methyl group to the 3'-most nucleotide of miRNAs as well as siRNAs from sense transgenes, hairpin transgenes, and transposons or repeat sequences, and a new class of siRNAs known as trans-acting siRNAs. PMID: 16111943
10. 3.1 A crystal structure of full-length HEN1 from Arabidopsis in complex with a 22-nucleotide small RNA duplex and cofactor product S-adenosyl-l-homocysteine PMID: 19812675

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KEGG: ath:AT4G20910

STRING: 3702.AT4G20910.1

UniGene: At.3574