norpA Antibody

1. This study demonstrated that NorpA and eya2 mutants with disrupted vision showed normal mating effects on sleep. PMID: 28851647
2. These results provide evidence for the existence of a unique dPIP5K dependent pool of PIP2 required for normal Drosophila phototransduction. PMID: 25633995
3. The positive feedback between PLCbeta and IP3R found here may represent a common feature of the inositol-lipid signaling PMID: 25673847
4. Taken together, these findings reveal that PLC function in Drosophila sweet-sensing neurons is a conserved molecular signaling pathway that confers attraction to fatty acids PMID: 24068941
5. This review prestnted the evidence the norpA mutation have significantly contributed to understanding the molecular and biochemical basis of phototransduction in Drosophila. PMID: 22283804
6. Light reception mediated by Rh5 and Rh6 must utilize either a different (nonretinal) phospholipase C-beta enzyme or alternative signaling mechanisms, at least in terms of clock-relevant photoreception PMID: 22306971
7. loss of the norpa gene product induces massive endocytosis of rhodopsin and arrestin in photoreceptors PMID: 11853766
8. Mutants of norpA, encoding phospholipase C beta (PLC beta), attenuate response to diuretic peptides of Drosophila melanogaster renal (Malpighian) tubules PMID: 12547945
9. norpA(P41) is directly involved in thermosensitivity PMID: 14766972
10. Of 47 norpA mutants screened for PLC protein content, all but one displayed drastically decreased amounts of protein suggesting that almost any mutational alteration has a deleterious effect on the integrity of the protein PMID: 15140198
11. Analysis of norpA inaE double mutants and severe inaE mutants defective in photoreceptor respponses to light shows that normal diacylglycerol lipase activity is required for the generation of physiologically meaningful photoreceptor responses. PMID: 18579079
12. the Galphaq-PLCbeta-Ca(2+)-DUOX-ROS signaling pathway acts as a bona fide first line of defense that enables gut epithelia to dynamically control yeast during the Drosophila life cycle PMID: 19289084

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KEGG: dme:Dmel_CG3620

STRING: 7227.FBpp0070618

UniGene: Dm.7394