Name: RDS2 Antibody
Brand: CUSABIO
SKU: CSB-PA324820XA01SVG

Product Details

Full Product Name	Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RDS2 Polyclonal antibody
Uniprot No.	P19541
Target Names	RDS2
Alternative Names	RDS2 antibody; YPL133C antibody; LPI12C antibody; Regulator of drug sensitivity 2 antibody
Raised in	Rabbit
Species Reactivity	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen	Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RDS2 protein
Immunogen Species	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate	Non-conjugated
Clonality	Polyclonal
Isotype	IgG
Purification Method	Protein A/G
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Tested Applications	ELISA, WB (ensure identification of antigen)
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables	① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control);
Quality Guarantee	① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive;
Lead Time	Made-to-order (14-16 weeks)

Target Background

Function (From Uniprot)	Transcription factor which regulates the expression of genes for gluconeogenesis, the TCA cycle, and glucose metabolism. Involved in the cell wall remodeling process and drug resistance.
Gene References into Functions	Rds2 binds to promoters of genes involved in gluconeogenesis, the glyoxylate shunt, and the TCA cycle as well as some genes encoding mitochondrial components or some involved in the stress response. There is an important overlap between the targets of Rds2 and Adr1. PMID: 22687600 A nonsynonymous polymorphism in RDS2 significantly affects oxidative stress survival in a clinical Saccharomyces cerevisiae isolate. PMID: 21515583 Data show that Rds2 has a dual function: it directly activates the expression of gluconeogenic structural genes while it represses the expression of negative regulators of this pathway. PMID: 17875938 Rds2 is indeed involved in the drug-sensitivity response and plays a role in determining osmotic sensitivity. PMID: 18683633
Subcellular Location	Cytoplasm. Nucleus.
Database Links	KEGG: sce:YPL133C STRING: 4932.YPL133C

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RDS2 Antibody

Code	CSB-PA324820XA01SVG
Size	Enquire
Have Questions?	Leave a Message or Start an on-line Chat