Rmdn3 Antibody

Code CSB-PA663665XA01MO
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Rmdn3 Polyclonal antibody
Uniprot No.
Target Names
Rmdn3
Alternative Names
Rmdn3; Fam82a2; Fam82c; Regulator of microtubule dynamics protein 3; RMD-3; mRMD-3; Protein FAM82A2; Protein FAM82C
Raised in
Rabbit
Species Reactivity
Mus musculus (Mouse)
Immunogen
Recombinant Mus musculus (Mouse) Rmdn3 protein
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis.
Gene References into Functions
  1. PTPIP51 as a therapeutic target for ischemic heart diseases. PMID: 28345618
  2. Protein interaction profile of PTPIP51 suggests a role in the memory formation in the hippocampus and cerebellum. PMID: 25496818
  3. PTPIP51(protein tyrosine phosphatase interacting protein 51) might serve as a linking protein in adipocyte metabolism by connecting the insulin receptor-triggered lipogenesis with the protein kinase A-dependent lipolysis. PMID: 23533724
  4. The interaction of PTPIP51 with 14-3-3beta, especially in trained individuals, hints to an involvement of PTPIP51 in the downstream regulation of insulin action. PMID: 21266951
  5. Includes the study of an upstream ORF in this gene, and shows that it functions to reduce protein levels by ~79%. PMID: 19372376
  6. The data presented here suggest a role of PTPIP51 in neuronal homeostasis, axonal growth, and transport. PMID: 19844996
  7. The PTPIP51 was integrated in signaling cascades regulating differentiation and apoptosis during eye development. PMID: 18084773

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Subcellular Location
Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
Protein Families
RMDN family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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