ttk Antibody

1. Ttk69 acts as a master repressor of enteroendocrine cell specification in Drosophila intestinal stem cell lineages. PMID: 26293304
2. The presence and timing of ttk69 expression are essential for somatic muscle development and required for the balance between founder cells and fusion-competent myoblasts. PMID: 24961800
3. Tramtrack69 functions as a developmental switch in Drosophila follicle cells where it is regulated by miR-7. PMID: 23325762
4. Ttk69 plays an instructive role in the growth of R7 photoreceptor axon terminals PMID: 23345225
5. The GBS two-component system CovS/CovR, which is the major acid response regulator in this organism, is required for survival inside the phagosome of macrophages. PMID: 22331428
6. discovered multiple roles of Ttk in the development of the tracheal system on the morphogenetic level. Here, we sought to identify some of the underlying genetic components that are responsible for the tracheal phenotypes of Ttk mutants PMID: 22216153
7. TTK69 is able to bind chromatin in the absence of NuRD, but targeting of NuRD is dependent on TTK69. PMID: 20733004
8. Tramtrack69 (TTK69) controls the fates and shapes of all columnar follicle cells PMID: 19934014
9. Using neural repression as an assay, we dissected functional domains of Ttk, confirming the importance of the bric-a-brac-tramtrack-broad complex (BTB) motif. PMID: 12204250
10. directly regulates the transcription of string and thereby cell proliferation PMID: 12447387
11. identification of a novel allele of tramtrack PMID: 12490195
12. the binding of TTK69 prevents the interaction of GAGA with the transcription machinery and compromises its activation potential PMID: 14701830
13. Tramtrack downregulates Cyclin E expression and is probably involved in the exit of cells from the cell cycle. PMID: 15829522
14. Results suggest that the involvement of Tramtrack in different steps of tube morphogenesis identifies it as a key player in tracheal development. PMID: 17881489
15. Sina protein may direct the degradation of the transcriptional repressor Tramtrack (Ttk) using two different mechanisms. PMID: 17962185
16. Deubiquitinylating enzyme UBP64 controls cell fate through stabilization of tkk. PMID: 18160715
17. Tramtrack (Ttk), a zinc-finger protein, is essential for the endocycle/gene amplification switch, is regulated negatively by Notch and positively by EcR. PMID: 18779369

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KEGG: dme:Dmel_CG1856

STRING: 7227.FBpp0085186

UniGene: Dm.1526