Human insulin-like growth factors binding protein 1,IGFBP-1 ELISA Kit

Code CSB-E04586h
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Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. P08833
Lead Time 3-5 working days
Abbreviation IGFBP1
Target Name insulin-like growth factor binding protein 1
Alias AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1, IGF-binding protein 1|alpha-pregnancy-associated endometrial globulin|amniotic fluid binding protein|binding protein-25|binding protein-26|binding protein-28|gr
Species Homo sapiens (Human)
Sample Types serum, plasma, tissue homogenates
Detection Range 1.56 ng/mL-100 ng/mL
Sensitivity 0.039 ng/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Signal Transduction
Protocol
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Assay Principle quantitative
Measurement Sandwich
Target Details This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
HGNC 5469
RGD 2872
MGI 96436
References
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Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
Subcellular Location Secreted
Database Links

HGNC: 5469

OMIM: 146730

KEGG: hsa:3484

STRING: 9606.ENSP00000275525

UniGene: Hs.642938

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