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Mouse Complement C2(C2) ELISA kit

Citations (1) Protocol
Code CSB-EL003658MO
Size 96T,5×96T,10×96T
Price Request a Quote
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Product Details

Target Name
complement component 2
Alternative Names
C2Complement C2 ELISA Kit; EC 3.4.21.43 ELISA Kit; C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment] ELISA Kit
Abbreviation
C2
Uniprot No.
P21180
Species
Mus musculus (Mouse)
Sample Types
serum, plasma, tissue homogenates
Detection Range
18.75 ng/mL-300 ng/mL
Sensitivity
18.75 ng/mL
Assay Time
1-5h
Sample Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Immunology
Assay Principle
quantitative
Measurement
Competitive
ELISA Data Analysis
ELISA Standard Curve & Curve Expert software
Troubleshooting
and FAQs
ELISA kit FAQs
Storage
Store at 2-8°C. Please refer to protocol.
Shelf Life
6 months
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx.
Description

This Mouse Complement C2 (C2) ELISA Kit was designed for the quantitative measurement of Mouse Complement C2 (C2) protein in serum, plasma, tissue homogenates. It is a Competitive ELISA kit, its detection range is 18.75 ng/mL-300 ng/mL and the sensitivity is 18.75 ng/mL.

Citations

Related Products

C2 Proteins

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Target Background

Function
(From Uniprot)
Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
Gene References into Functions
  1. Data indicate that activation of C5 in experimental cerebral malaria likely occurs via coagulation enzymes of the extrinsic protease pathway. PMID: 22689574
  2. The more pronounced lack of complement activation in Bf/C2-/- mice leads to uncontrolled infection due to an opsonophagocytic defect PMID: 18672286
Subcellular Location
Secreted.
Protein Families
Peptidase S1 family
Database Links
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Reward For Reviews
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Related pathways
Complement and coagulation cascades
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