The rat CD68 Elisa kit is suitable for quantitatively measuring human MLCK in serum, plasma, or tissue homogenates. This assay employs the sandwich enzyme immunoassay technique and enzyme-substrate chromogenic reaction. The color develops positively to the amount of MLCK in samples. The color development is stopped and the intensity of the color is measured. This kit displays many advantages, including high sensitivity, strong specificity, good linearity, high precision and recovery, and lot-to-lot consistency.
CD68 is a heavily glycosylated glycoprotein highly expressed in macrophages and other mononuclear phagocytes. It is commonly used as a histochemical/cytochemical marker of inflammation associated with the involvement of human monocytes and macrophages. CD68 alone or in combination with other cell markers of tumor-associated macrophages showed a good predictive value as a prognostic marker of survival in cancer patients. CD68 is mainly located in the endosomal/lysosomal compartment but can rapidly shuttle to the cell surface. It can bind oxLDL, phosphatidylserine, and apoptotic cells and serve as a receptor for malaria sporozoite in liver infection.