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| Code | CSB-AP001811HU |
| Product Type | Interleukin |
| Size |
$112Purchase it in Cusabio online store (Shop online in the US. Customers outside the US, please order from local distributors.) |
| Uniprot No. | P29459 |
| Image |
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| Storage Buffer | 0.2 μm filtered PBS, pH 7.4 ,lyophilized |
| Alias | IL-12A, CLMF p35, IL-12 subunit p35, NK cell stimulatory factor chain 1, NKSF1 |
| Species | Homo sapiens (Human) |
| Biological_Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using PHA-activated human T lymphoblasts is less than 0.05 ng/ml, corresponding to a specific activity of >2.0x107 IU/mg. |
| Purity | >95% as determined by SDS-PAGE and HPLC. |
| Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
| Sequence | p35 Subunit: RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNAS p40 Subunit: IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSATVICRK NASISVRAQD RYYSSSWSEW ASVPCS |
| Research Area | Immunology |
| Source | Mammalian cell |
| Gene Names | IL12A |
| Expression Region | 23-219aa&23-328aa |
| Tag Info | Tag-Free |
| Mol. Weight | 75.0 kDa |
| Protein Description | Full Length of Mature Protein |
| PubMed ID | 1673147; 1674604; 16641997; 2204066; 1374259; 16548883; 10899108 |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. |
| Subcellular Location | Secreted |
| Protein Families | IL-6 superfamily |
| Database Links |
HGNC: 5969 OMIM: 161560 KEGG: hsa:3592 STRING: 9606.ENSP00000303231 UniGene: Hs.673 |
| Pathway |
Jak-STAT signaling pathway
Th1 and Th2 cell differentiation Toll-like receptor signaling pathway |
IL12A Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA16819A0Rb | IL12A Antibody | Human | ELISA, IHC |
IL12A Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA16819B0Rb | IL12A Antibody, HRP conjugated | Human | ELISA |
| CSB-PA16819C0Rb | IL12A Antibody, FITC conjugated | Human | ELISA |
| CSB-PA16819D0Rb | IL12A Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA004736 | IL12A Antibody | Human | WB,ELISA |
| CSB-PA005776 | IL12A Antibody | Human | WB,ELISA |
| CSB-PA877335 | IL12A Antibody | Human | ELISA,IHC |
IL12A Antibodies for
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA009581 | IL12A Antibody | Human, Mouse, Rat | WB, IHC, ICC, ELISA |
IL12A Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-AP004691HU | Recombinant Human Interleukin-12(IL12) (Active) | Mammalian cell |
| CSB-YP011586HU CSB-EP011586HU CSB-BP011586HU CSB-MP011586HU |
Recombinant Human Interleukin-12 subunit alpha(IL12A) | Yeast E.coli Baculovirus Mammalian cell |
IL12A ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL011586HU | Human Interleukin-12 subunit alpha(IL12A) ELISA kit | serum, plasma, cell culture supernates | 3.9 pg/mL |
Recombinant Human Ecto-NOX disulfide-thiol exchanger 2(ENOX2)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human T-complex protein 1 subunit beta(CCT2)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Ras-related protein Ral-B(RALB)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Protein phosphatase 1A(PPM1A)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Macaca mulatta Interleukin-10(IL10)
Express system: Yeast
Species: Macaca mulatta (Rhesus macaque)
