Greater than 95% as determined by SDS-PAGE.
Less than 1.0 EU/ug as determined by LAL method.
Measured by its binding ability in a functional ELISA. Immobilized NRG1 at 2 μg/ml can bind human ERBB3(CSB-MP007765HU), the EC50 is 18.24-23.66 ng/ml.
Homo sapiens (Human)
Target Protein Sequence
Partial of Isoform 6
Note: We will preferentially ship the format that
we have in stock, however, if you have any special requirement for the format, please remark your
requirement when placing the order, we will prepare according to your demand.
Lyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized
form is 12 months at -20°C/-80°C.
3-7 business days
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
A construct encoding COOH-terminally 6xHis-tagged human NRG1 was expressed in mammalian cells. The resulting protein is the recombinant NRG1 protein containing amino acid sequence 20-247 of human NRG1. The purity of this NRG1 protein is greater than 95% determined by SDS-PAGE. A molecular mass band of 40 kDa was presented on the gel under reducing conditions. It contains low levels of endotoxin, less than 1.0 EU/ug determined by the LAL method. And this NRG1 protein has also been tested as an active protein through a functional ELISA. It binds to the human ERBB3with an EC50 of 18.24-23.66 ng/ml. It is available now.
NRG1 is a trophic factor generated by nerves and muscles. Interaction with its tyrosine kinase transmembrane receptors ErbB1-4, NRG1 regulates myogenesis, muscle spindle development and maintenance, neural development, cardiovascular system development, adult heart functions, glucose transport, mitochondrial oxidative capacity, and acetylcholine receptor expression.