Recombinant Human Thymosin beta-4 protein(TMSB4X) (Active)


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Code CSB-AP000381HU
Product Type Other
Size US$112Purchase it in Cusabio online store
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Uniprot No. P62328
Lead Time 5-10 business days
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Storage Buffer 0.2 μm filtered 20 mM PB, pH 7.4, 150mM NaCl ,lyophilized
Alias T beta-4
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The biological activity determined by its ability to produce a protective effect against hydrogen peroxide in primary lung fibroblasts is in a concentration range of 0.5 - 10 μg/ml.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence SDKPDMAEIE KFDKSKLKKT ETQEKNPLPS KETIEQEKQA GES
Research Area Signal Transduction
Source E.coli
Gene Names TMSB4X
Expression Region 2-44aa
Tag Info Tag-Free
Mol. Weight 4.9 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3500230; 16010977; 1999398; 6548414; 18669648; 19608861; 20068231; 21269460; 21406692; 22223895; 10848969; 23009842
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Function Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
Subcellular Location Cytoplasm, cytoskeleton
Protein Families Thymosin beta family
Tissue Specificity Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells.
Database Links

HGNC: 11881

OMIM: 300159

KEGG: hsa:7114

STRING: 9606.ENSP00000370007

UniGene: Hs.437277

Pathway Regulation of actin cytoskeleton

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