A4GALT Antibody

Datasheet
Code CSB-PA868276ESR1HU
Size US$167Purchase it in Cusabio online store
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Uniprot No. Q9NPC4
Image
  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA868276ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA868276ESR1HU at dilution of 1:100

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human Lactosylceramide 4-alpha-galactosyltransferase protein (244-353AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Relevance Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.
Form Liquid
Conjugate Non-conjugated
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias Lactosylceramide 4-alpha-galactosyltransferase (EC 2.4.1.228) (Alpha-1,4-N-acetylglucosaminyltransferase) (Alpha-1,4-galactosyltransferase) (Alpha4Gal-T1) (CD77 synthase) (Globotriaosylceramide synthase) (Gb3 synthase) (P1/Pk synthase) (UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase), A4GALT, A14GALT A4GALT1
Immunogen Species Human
Research Area Cardiovascular
Target Names A4GALT
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.
Subcellular Location Golgi apparatus membrane, Single-pass type II membrane protein
Protein Families Glycosyltransferase 32 family
Tissue Specificity Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta.
Database Links

HGNC: 18149

OMIM: 111400

KEGG: hsa:53947

STRING: 9606.ENSP00000249005

UniGene: Hs.105956

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