ABCC3 Antibody

Datasheet
Code CSB-PA001062LA01HU
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Size US$299
Uniprot No. O15438
Image
  • Immunofluorescent analysis of A549 cells using CSB-PA001062LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunogen Recombinant Human Canalicular multispecific organic anion transporter 2 protein (827-953AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IF; Recommended dilution: IF:1:50-1:200
Relevance May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity).
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3), ABCC3, CMOAT2 MLP2 MRP3
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Immunofluorescence (IF) Protocol
Research Area Signal Transduction
Target Names ABCC3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity).
Subcellular Location Membrane, Multi-pass membrane protein
Protein Families ABC transporter superfamily, ABCC family, Conjugate transporter (TC 3.A.1.208) subfamily
Tissue Specificity Mainly expressed in the liver. Also expressed in small intestine, colon, prostate, testis, brain and at a lower level in the kidney.
Database Links

HGNC: 54

OMIM: 604323

KEGG: hsa:8714

STRING: 9606.ENSP00000285238

UniGene: Hs.463421

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