BDH2 Antibody

Code CSB-PA874814LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA874814LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA874814LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) BDH2 Polyclonal antibody
Uniprot No.
Target Names
BDH2
Alternative Names
3 hydroxybutyrate dehydrogenase type 2 antibody; 3-hydroxybutyrate dehydrogenase type 2 antibody; BDH 2 antibody; BDH2 antibody; BDH2_HUMAN antibody; Dehydrogenase/reductase (SDR family) member 6 antibody; Dehydrogenase/reductase SDR family member 6 antibody; DHRS6 antibody; EFA6R antibody; FLJ13261 antibody; Oxidoreductase ucpA antibody; PRO20933 antibody; R beta hydroxybutyrate dehydrogenase antibody; R-beta-hydroxybutyrate dehydrogenase antibody; SDR15C1 antibody; Short chain dehydrogenase/reductase family 15C member 1 antibody; UCPA OR antibody; UNQ6308 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human 3-hydroxybutyrate dehydrogenase type 2 protein (1-245AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The BDH2 Antibody (Product code: CSB-PA874814LA01HU) is Non-conjugated. For BDH2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA874814LB01HU BDH2 Antibody, HRP conjugated ELISA
FITC CSB-PA874814LC01HU BDH2 Antibody, FITC conjugated
Biotin CSB-PA874814LD01HU BDH2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function
Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron assimilation and homeostasis. Plays a role in susceptibility to bacterial infection by providing an assimilable source of iron that is exploited by pathogenic bacteria. Also acts as a 3-hydroxybutyrate dehydrogenase.
Gene References into Functions
  1. High expression level of BDH2 is associated with esophageal squamous cell carcinoma. PMID: 26799587
  2. intracellular expression in macrophages is downregulated by stress and inflammation PMID: 25762501
  3. BDH2 expression is an independent poor prognostic factor for CN-AML, with an anti-apoptotic role. Patients with high BDH2 expression have relatively shorter overall survival and a low complete response rate. PMID: 23941109
  4. Iron-mediated post-transcriptional regulation of hBDH2 controls mitochondrial iron homeostasis in human cells. PMID: 22527885
  5. Data show that the ketone body metabolizing enzymes BDH1, BDH2, OXCT1 and ACAT1 were expressed at the mRNA and protein level in all glioma cell lines. PMID: 21791085
  6. DHRS6 is an orphan short chain dehydrogenase/ reductase enzyme PMID: 16380372

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Subcellular Location
Cytoplasm.
Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Tissue Specificity
Detected in liver (at protein level).
Database Links

HGNC: 32389

KEGG: hsa:56898

STRING: 9606.ENSP00000296424

UniGene: Hs.124696

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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