COX19 Antibody

Code CSB-PA586799
Size US$166
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Image
  • The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA586799(COX19 Antibody) at dilution 1/50. (Original magnification: ×200)
  • The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA586799(COX19 Antibody) at dilution 1/50. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
COX19
Alternative Names
COX19Cytochrome c oxidase assembly protein COX19 antibody; hCOX19 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human COX19
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:10000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for the transduction of an SCO1-dependent redox signal from the mitochondrion to ATP7A to regulate cellular copper homeostasis. May be required for the assembly of mitochondrial cytochrome c oxidase.
Gene References into Functions
  1. COX19 is necessary for the transduction of a SCO1-dependent mitochondrial redox signal that regulates ATP7A-mediated cellular copper efflux. PMID: 23345593
  2. Both hCox18p and hCox19p present significant amino acid identity with the corresponding yeast polypeptides and reveal highly conserved functional domains. PMID: 16212937
Subcellular Location
Cytoplasm, cytosol. Mitochondrion intermembrane space. Mitochondrion.
Protein Families
COX19 family
Tissue Specificity
Ubiquitously expressed. Highly expressed in skeletal muscle.
Database Links

HGNC: 28074

OMIM: 610429

KEGG: hsa:90639

STRING: 9606.ENSP00000342015

UniGene: Hs.121593

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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