DPYSL4 Antibody, Biotin conjugated

Code CSB-PA007172LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DPYSL4 Polyclonal antibody
Uniprot No.
Target Names
DPYSL4
Alternative Names
Collapsin response mediator protein 3 antibody; CRMP 3 antibody; CRMP-3 antibody; CRMP3 antibody; Dihydropyrimidinase like 4 antibody; Dihydropyrimidinase related protein 4 antibody; Dihydropyrimidinase-related protein 4 antibody; DPYL4_HUMAN antibody; DPYSL4 antibody; DRP 4 antibody; DRP-4 antibody; DRP4 antibody; ULIP 4 antibody; ULIP-4 antibody; ULIP4 antibody; UNC33 like phosphoprotein 4 antibody; UNC33-like phosphoprotein 4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Dihydropyrimidinase-related protein 4 protein (280-560AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
Gene References into Functions
  1. DPYSL4 plays a key role in the tumor-suppressor function of p53 by regulating oxidative phosphorylation and the cellular energy supply via its association with mitochondrial supercomplexes, possibly linking to the pathophysiology of both cancer and obesity. PMID: 30061407
  2. DPYSL4 is a novel apoptosis-inducible factor controlled by p53 in response to DNA damage PMID: 20499313
  3. Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain. PMID: 11771764
Subcellular Location
Cytoplasm.
Protein Families
Metallo-dependent hydrolases superfamily, Hydantoinase/dihydropyrimidinase family
Database Links

HGNC: 3016

OMIM: 608407

KEGG: hsa:10570

STRING: 9606.ENSP00000339850

UniGene: Hs.100058

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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