IFT27 Antibody

Code CSB-PA874822LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA874822LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA874822LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) IFT27 Polyclonal antibody
Uniprot No.
Target Names
IFT27
Alternative Names
BBS19 antibody; Ift27 antibody; IFT27_HUMAN antibody; Intraflagellar transport 27 antibody; Intraflagellar transport protein 27 homolog antibody; Putative GTP binding protein RAY like antibody; Putative GTP-binding protein RAY-like antibody; Rab like protein 4 antibody; RAB member of RAS oncogene family like 4 antibody; Rab-like protein 4 antibody; RAYL antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Intraflagellar transport protein 27 homolog protein (1-186AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The IFT27 Antibody (Product code: CSB-PA874822LA01HU) is Non-conjugated. For IFT27 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA874822LB01HU IFT27 Antibody, HRP conjugated ELISA
FITC CSB-PA874822LC01HU IFT27 Antibody, FITC conjugated
Biotin CSB-PA874822LD01HU IFT27 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6. Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6. Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation.
Gene References into Functions
  1. Study coupled human genetics with functional validation in zebrafish and identified IFT27 as a novel BBS gene (BBS19). PMID: 24488770
Involvement in disease
Bardet-Biedl syndrome 19 (BBS19)
Subcellular Location
Cell projection, cilium. Cytoplasm. Cell projection, cilium, flagellum.
Protein Families
Small GTPase superfamily, Rab family
Database Links

HGNC: 18626

OMIM: 615870

KEGG: hsa:11020

STRING: 9606.ENSP00000393541

UniGene: Hs.415172

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