KLF3 Antibody

Datasheet

Code	CSB-PA012393DSR2HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA012393DSR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA012393DSR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA012393DSR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) KLF3 Polyclonal antibody

Uniprot No.

P57682

Target Names

KLF3

Alternative Names

Basic krueppel-like factor antibody; Basic Kruppel like factor antibody; BKLF3 antibody; CACCC box binding protein BKLF antibody; CACCC-box-binding protein BKLF antibody; Klf3 antibody; KLF3_HUMAN antibody; Krueppel-like factor 3 antibody; Kruppel like factor 3 (basic) antibody; MGC48279 antibody; TEF-2 antibody; TEF2 antibody; Transcript ch138 antibody; Zinc finger protein 741 antibody; ZNF741 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Krueppel-like factor 3 protein (1-240AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis.

Gene References into Functions

Low KLF3 expression is associated with colorectal cancer. PMID: 28423541
Among the mechanosensitive genes, the two transcription factors, HoxA5 and Klf3, contain cAMP-response-elements methylation of which could serve as a mechanosensitive master switch in gene expression in atherosclerosis. (Review) PMID: 25979369
Klf-3 expression is downregulated in human metastatic sarcomas, and Klf-3 levels negatively correlate with miR-182 expression. PMID: 26314219
A feedback loop consisting of microRNA 23a/27a and the beta-like globin suppressors KLF3 and SP1 regulates globin gene expression. PMID: 23918807
B cell differentiation is significantly impaired in the bone marrow, spleen, and peritoneal cavity of Klf3 null mice; the defects are cell autonomous. PMID: 22003205
Low KLF3 is associated with acute myeloid leukemia. PMID: 21470678
KLF3 is an important regulator of several biological processes, including adipogenesis, erythropoiesis, and B cell development. (Review) PMID: 21360637
The recruitment of CtBP and sumoylation are required for full repression by BKLF. PMID: 15684403

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Subcellular Location

Nucleus.

Protein Families

Krueppel C2H2-type zinc-finger protein family

Database Links

HGNC: 16516

OMIM: 609392

KEGG: hsa:51274

STRING: 9606.ENSP00000261438

UniGene: Hs.298658

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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