PEBP4 Antibody

1. PEBP4 was associated with the development and invasion of gastric cancer cells through activation of the PI3K/Akt signaling pathway PMID: 28193908
2. knockdown of PEBP4 inhibited hypoxia-induced epithelial-to-mesenchymal transition in prostate cancer cells. PMID: 27261570
3. this study suggested that PEBP4 might promote the progression of pancreatic ductal adenocarcinoma PMID: 26311050
4. Increased expression of phosphatidylethanolamine-binding protein 4 strongly associates with gliomas grade. PMID: 26725095
5. PEBP4 is a secreted protein and has multiple functions, including a role in Akt phosphorylation. PMID: 27033522
6. Increased miR-15b expression in lung adenocarcinoma patients treated with cisplatin-based chemotherapy was correlated with low expression of PEBP4, decreased sensitivity to cisplatin and poor prognosis. PMID: 25721211
7. concluded that hPEBP4, specifically expressed in rectal cancer cells, is associated with radioresistance of rectal cancer PMID: 24594691
8. overexpression of PEBP4, which we show to be a target of miR-34a, reduces the sensitivity of lung cancer cells to cisplatin PMID: 25038915
9. in human breast cancer hPEBP4 is a novel and clinically relevant metastasis accelerator gene PMID: 24276246
10. Human PEBP4 expression correlates negatively with estrogen and progesterone receptors in endometrial carcinoma. PMID: 23818363
11. hPEBP4 knockdown potentiated the chemosensitization of the rituximab in B-cell lymphoma cells by regulating the expression of Bcl-xl, Cycline E, p21(waf/cip1) and p53 and the activation of caspase-3 and caspase-9. PMID: 23451095
12. the independent predictive values of hPEBP4 in response of rectal cancer to preoperative radiotherapy, are reported. PMID: 22801881
13. PEBP4 enhanced cell proliferation and invasion ability and inhibited apoptosis. Decreased PEBP4 expression may play a role in the reduced invasion ability and increased apoptosis of the human non-small cell lung cancer cell line HCC827. PMID: 22983920
14. PEBP4 over-expression may promote the invasion and metastasis of non-small cell lung cancer. PMID: 22076923
15. The over-expression of PEBP4 protein may be related to the tumorigenesis, development, metastasis, and invasion of colorectal cancer. PMID: 22125029
16. Data show that PEBP4 protein overexpression was associated with the occurrence, invasion, and metastasis of lung squamous cell carcinoma. PMID: 21887552
17. hPEBP4 inhibits proteasome-dependent ERalpha degradation through the Src pathway. PMID: 20460377
18. hPEBP4 promotes cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK, and PE externalization. PMID: 15302887
19. Silencing of hPEBP4, an important potential target, may be a promising approach for the treatment of ovarian cancer. PMID: 16865237
20. Data show that PEBP4 participates in the control of muscle cell differentiation by modulating the activity of MEK and ERK. PMID: 19197339

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HGNC: 28319

OMIM: 612473

KEGG: hsa:157310

STRING: 9606.ENSP00000256404

UniGene: Hs.491242